PD-L1 antibody (AA 252-290)

Catalog No. ABIN6243056

This Rabbit Polyclonal antibody specifically detects PD-L1 in WB. It exhibits reactivity toward Human.

Quick Overview for PD-L1 antibody (AA 252-290) (ABIN6243056)

Target: PD-L1 (CD274 (PD-L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PD-L1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB58901

Product Details anti-PD-L1 Antibody

Binding Specificity: AA 252-290

Predicted Reactivity: H

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PD L1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 252-290 amino acids from the human region of human PD L1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PD-L1

Target: PD-L1 (CD274 (PD-L1))

Alternative Name: PD L1

Background: Involved in the costimulatory signal, essential for T- cell proliferation and production of IL10 and IFNG, in an IL2- dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

Molecular Weight: 33275

UniProt: Q9NZQ7

Pathways: Cancer Immune Checkpoints